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YH-53

Product Specifications

CAS Number

1471484-62-4

Target

Others, SARS-CoV

Related Pathways

Others, Microbiology/Virology

Bioactivity

YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl ketone structure, significantly inhibits SARS-CoV-2 replication, highlighting its potential in COVID-19 research [1] [2].

Smiles

COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1

Molecular Formula

C30H33N5O5S

Molecular Weight

575.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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