MAK-683 hydrochloride
Product Specifications
CAS Number
2170606-94-5
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
MAK683 hydrochloride embryonic ectodermal development (EED) inhibitor, also a potent PRC2 inhibitor, blocked cancer cell proliferation (IC50=1.014nM), with IC50 values of 59, 26, and 89 nM measured in EED Alphascreen, ELISA, and LC-MS assays, respectively.
Smiles
FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C(C=CC=N4)=C4C)C5=NN=CN35.Cl
Molecular Formula
C20H18ClFN6O
Molecular Weight
412.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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