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MAK-683 hydrochloride

Product Specifications

CAS Number

2170606-94-5

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

MAK683 hydrochloride embryonic ectodermal development (EED) inhibitor, also a potent PRC2 inhibitor, blocked cancer cell proliferation (IC50=1.014nM), with IC50 values of 59, 26, and 89 nM measured in EED Alphascreen, ELISA, and LC-MS assays, respectively.

Smiles

FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C(C=CC=N4)=C4C)C5=NN=CN35.Cl

Molecular Formula

C20H18ClFN6O

Molecular Weight

412.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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