MAK-683 hydrochloride
Product Specifications
CAS Number
2170606-94-5
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
MAK683 hydrochloride embryonic ectodermal development (EED) inhibitor, also a potent PRC2 inhibitor, blocked cancer cell proliferation (IC50=1.014nM), with IC50 values of 59, 26, and 89 nM measured in EED Alphascreen, ELISA, and LC-MS assays, respectively.
Smiles
FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C(C=CC=N4)=C4C)C5=NN=CN35.Cl
Molecular Formula
C20H18ClFN6O
Molecular Weight
412.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2150336-01 0.1 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details MBS2150336-02 0.2 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details 
MBS2150336-03 0.5 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details MBS2150336-04 1 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details MBS2150336-05 5 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details MBS2150336-06 5x 5 mL
APC_Cy7-Linked Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO)
Ask
View Details