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Esuberaprost Sodium

Product Specifications

CAS Number

1044040-56-3

Target

Others, PDGFR, VEGFR, Apoptosis

Related Pathways

Angiogenesis, Others, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

Famitinib (SHR1020) is a potent orally active multi-targeted kinase inhibitor that effectively inhibits the activity of c-kit, VEGFR-2, and PDGFRβ with IC50 values of 2.3 nM, 4.7 nM, and 6.6 nM, respectively [1]. It demonstrates remarkable antitumor properties in human gastric cancer cells and xenografts, inducing apoptosis [2].

Smiles

CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O

Molecular Formula

C23H27FN4O2

Molecular Weight

410.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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