Esuberaprost Sodium
Product Specifications
CAS Number
1044040-56-3
Target
Others|||PDGFR|||VEGFR|||Apoptosis
Related Pathways
Angiogenesis|||Others|||Tyrosine Kinase/Adaptors|||Apoptosis
Bioactivity
Famitinib (SHR1020) is a potent orally active multi-targeted kinase inhibitor that effectively inhibits the activity of c-kit, VEGFR-2, and PDGFR? with IC50 values of 2.3 nM, 4.7 nM, and 6.6 nM, respectively [1]. It demonstrates remarkable antitumor properties in human gastric cancer cells and xenografts, inducing apoptosis [2].
Smiles
CCN(CC)CCN1CCc2[nH]c(\C=C3/C(=O)Nc4ccc(F)cc34)c(C)c2C1=O
Molecular Formula
C23H27FN4O2
Molecular Weight
410.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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