PD-1/PD-L1-IN-9
Product Specifications
CAS Number
2628506-54-5
Target
PD-1/PD-L1
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation
Purity
0.9992
Bioactivity
PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in vivo in a CT26 mouse model.
Smiles
COc1nc(ccc1CNCCO)-c1cccc(c1C)-c1ccccc1
Molecular Formula
C22H24N2O2
Molecular Weight
348.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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