CU-115
Product Specifications
CAS Number
2471982-20-2
Target
TLR
Related Pathways
Immunology/Inflammation
Purity
>99.99%
Bioactivity
CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 μM and =>50 μM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.
Smiles
Fc1cccc(I)c1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1
Molecular Formula
C21H11F7INO2
Molecular Weight
569.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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