Triciferol
Product Specifications
CAS Number
957214-00-5
Target
Others, Vitamin, HDAC
Related Pathways
DNA Damage/DNA Repair, Metabolism, Chromatin/Epigenetic, Others
Bioactivity
Triciferol acts as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC 50 =87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Triciferol also exhibits efficacious antiproliferative and cytotoxic activities in cancer cell models in vitro [1].
Smiles
[H][C@@]12CC[C@H]([C@H](C)\C=C(/C)\C=C\C(=O)NO)[C@@]1(C)CCC\C2=C/C=C1C[C@@H](O)C[C@H](O)C1
Molecular Formula
C26H39NO4
Molecular Weight
429.591
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K070 1.0 µg
CRISPR Scrambled sgRNA All-in-One AAV vector (with saCas9)
Sign In for Pricing
View Details 
