I-BET567
Product Specifications
CAS Number
1887237-54-8
Target
Epigenetic Reader Domain, Others
Related Pathways
Chromatin/Epigenetic, Others
Purity
0.998
Bioactivity
I-BET567, a potent pan-BET inhibitor with oral activity, demonstrates pIC50 values of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. This compound has exhibited efficacy in mouse models of oncology and inflammation [1].
Smiles
C[C@H]1C[C@@H](Nc2ncc(Cl)cn2)c2cc(ccc2N1C(C)=O)C(N)=O
Molecular Formula
C17H18ClN5O2
Molecular Weight
359.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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