I-BET567

Product Specifications

CAS Number

1887237-54-8

Target

Epigenetic Reader Domain|||Others

Related Pathways

Chromatin/Epigenetic|||Others

Purity

0.998

Bioactivity

I-BET567, a potent pan-BET inhibitor with oral activity, demonstrates pIC50 values of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. This compound has exhibited efficacy in mouse models of oncology and inflammation [1].

Smiles

C[C@H]1C[C@@H](Nc2ncc(Cl)cn2)c2cc(ccc2N1C(C)=O)C(N)=O

Molecular Formula

C17H18ClN5O2

Molecular Weight

359.81

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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