GSK3685032

Product Specifications

CAS Number

2170137-61-6

Target

DNA Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9949

Bioactivity

GSK3685032 is a non-covalent and selective DNMT1 inhibitor (IC50 = 36 nM) . The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits cancer cell growth.

Smiles

CCc1c(C#N)c(SC(C(N)=O)c2ccccc2)nc(N2CCC(N)CC2)c1C#N

Molecular Formula

C22H24N6OS

Molecular Weight

420.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NB100-2527AF405 0.1 mL

Rabbit Polyclonal LOX Antibody [Alexa Fluor 405]

Ask

View Details

PH0169M24 100 µg

SARS-CoV-2 Spike S1+S2 (D80A, LAL242-244 deletion, R246I, K417N, E484K, N501Y, D614G, A701V) Protein (ECD, His Tag)

Ask

View Details

MBS8534842-01 0.1 mL

BECN1

Ask

View Details

MBS8534842-02 0.1 mL (AF405L)

BECN1

Ask

View Details

MBS8534842-03 0.1 mL (AF405S)

BECN1

Ask

View Details

MBS8534842-04 0.1 mL (AF610)

BECN1

Ask

View Details