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TGFβRI-IN-3

Product Specifications

CAS Number

2763602-67-9

Target

TGF-beta/Smad

Related Pathways

Stem Cells

Purity

0.9985

Bioactivity

TGFβRI-IN-3 is a highly selective TGFβR1 inhibitor with an IC50 of 0.79 nM and exhibits 2000-fold selectivity against MAP4K4, showing potential applications in immuno-oncology [1].

Smiles

N(C=1C2=C(C=C(C=C2)C3=CC=C(S(C)(=O)=O)C=C3)N=CC1)C=4C=C(N=CC4)C5=CC(C)=CC=C5

Molecular Formula

C28H23N3O2S

Molecular Weight

465.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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