Venadaparib
Product Specifications
CAS Number
1681017-83-3
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Purity
0.9986
Bioactivity
Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSBs) and can be used in solid tumor research.
Smiles
Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CC(CNC2CC2)C1
Molecular Formula
C23H23FN4O2
Molecular Weight
406.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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