Alcian Blue 8GX

Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues[1][2][3][4].

Product Specifications

CAS Number

[33864-99-2]

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/alcian-blue-8gx.html

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN(C)/C(SCC(C=C1)=CC2=C1/C3=N/C(C4=C/5C=CC(CS/C(N(C)C)=[N+](C)\C)=C4)=NC5=N/C6=C(C=C(CS/C(N(C)C)=[N+](C)\C)C=C7)C7=C8N6[Cu]N3/C2=N\C9=N/C(C%10=C9C=CC(CS/C(N(C)C)=[N+](C)/C)=C%10)=N\8)=[N+](C)\C.[Cl-].[Cl-].[Cl-].[Cl-]

Molecular Formula

C56H68Cl4CuN16S4

Molecular Weight

1298.86

Precautions

H315, H319, H335

References & Citations

[1]Hiroki Ueharu, et al. Isolation and Culture of Cranial Neural Crest Cells from the First Branchial Arch of Mice. Bio Protoc. 2022 Apr 5;12 (7) :e4371.|[2]J Tas, et al. The Alcian blue and combined Alcian blue--Safranin O staining of glycosaminoglycans studied in a model system and in mast cells. Histochem J. 1977 Mar;9 (2) :205-30.|[3]Brian G Redfern, et al. An alternative Alcian Blue dye variant for the evaluation of fetal cartilage. Birth Defects Res B Dev Reprod Toxicol. 2007 Jun;80 (3) :171-6.|[4]Yuan Fang Li, et al. Determination of Proteins Based on Their Resonance Light Scattering Enhancement Effect on Alcian Blue 8GX. Original Papers. 2000 Dec; VOL.16