MRTX1133
Product Specifications
CAS Number
2621928-55-8
Target
Ras, Kras
Related Pathways
MAPK, GPCR/G Protein
Purity
0.996
Bioactivity
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
Smiles
Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(C#C)c(F)ccc2c1
Molecular Formula
C33H31F3N6O2
Molecular Weight
600.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
I7661-25JX-AP 100 µL
Insulin Receptor, alpha (IRa) (BSA & Azide Free) (AP) discontinued
Sign In for Pricing
View Details bs-20068R-BF647-TR 20 µL
UGT1A7 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details 