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Pim-1/2 kinase inhibitor 1

Product Specifications

CAS Number

6320-51-0

Target

Pim

Related Pathways

JAK/STAT signaling|||Chromatin/Epigenetic

Purity

0.9989

Bioactivity

Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1].

Smiles

COc1ccc(C=C2SC(=O)NC2=O)cc1

Molecular Formula

C11H9NO3S

Molecular Weight

235.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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