Pim-1/2 kinase inhibitor 1
Product Specifications
CAS Number
6320-51-0
Target
Pim
Related Pathways
JAK/STAT signaling|||Chromatin/Epigenetic
Purity
0.9989
Bioactivity
Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1].
Smiles
COc1ccc(C=C2SC(=O)NC2=O)cc1
Molecular Formula
C11H9NO3S
Molecular Weight
235.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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