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SHR0302

Product Specifications

CAS Number

1445987-21-2

Target

JAK, Apoptosis

Related Pathways

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Apoptosis, Stem Cells, Angiogenesis

Purity

0.9911

Bioactivity

SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2) .

Smiles

[H][C@@]12C[C@H](C[C@]1([H])CN(C2)C(=O)Nc1nc(OC)ns1)N(C)c1ncnc2[nH]ccc12

Molecular Formula

C18H22N8O2S

Molecular Weight

414.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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