SHR0302
Product Specifications
CAS Number
1445987-21-2
Target
JAK, Apoptosis
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Apoptosis, Stem Cells, Angiogenesis
Purity
0.9911
Bioactivity
SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2) .
Smiles
[H][C@@]12C[C@H](C[C@]1([H])CN(C2)C(=O)Nc1nc(OC)ns1)N(C)c1ncnc2[nH]ccc12
Molecular Formula
C18H22N8O2S
Molecular Weight
414.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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