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Iptacopan hydrochloride

Product Specifications

CAS Number

1646321-63-2

Target

Complement System

Related Pathways

Immunology/Inflammation

Purity

0.9989

Bioactivity

Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.

Smiles

Cl.CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O

Molecular Formula

C25H31ClN2O4

Molecular Weight

458.98

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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