NRX-252262
Product Specifications
CAS Number
2438637-61-5
Target
Molecular Glues, E1/E2/E3 Enzyme, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, PROTAC, Stem Cells, Ubiquitination
Purity
0.9987
Bioactivity
NRX-252262 is a potent enhancer of the interaction between β-Catenin and its cognate E3 ligase, SCFβ-TrCP, inducing mutant β-Catenin degradation (EC50: 3.8 nM) .
Smiles
COc1cc2CN(Cc2cc1OC)C(=O)c1c(Sc2c(Cl)cccc2Cl)cc([nH]c1=O)C(F)(F)F
Molecular Formula
C23H17Cl2F3N2O4S
Molecular Weight
545.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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