NRX-252262

Product Specifications

CAS Number

2438637-61-5

Target

Molecular Glues|||E1/E2/E3 Enzyme|||Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling|||PROTAC|||Stem Cells|||Ubiquitination

Purity

0.9987

Bioactivity

NRX-252262 is a potent enhancer of the interaction between ?-Catenin and its cognate E3 ligase, SCF?-TrCP, inducing mutant ?-Catenin degradation (EC50: 3.8 nM) .

Smiles

COc1cc2CN(Cc2cc1OC)C(=O)c1c(Sc2c(Cl)cccc2Cl)cc([nH]c1=O)C(F)(F)F

Molecular Formula

C23H17Cl2F3N2O4S

Molecular Weight

545.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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