NITD-349
NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.
Product Specifications
CAS Number
1473450-62-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/NITD-349.html
Purity
98.98
Solubility
DMSO : ≥ 310 mg/mL
Smiles
O=C(C(N1)=CC2=C1C=C(F)C=C2F)NC3CCC(C)(C)CC3
Molecular Formula
C17H20F2N2O
Molecular Weight
306.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Rao SP, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Sci Transl Med. 2013 Dec 4;5 (214) :214ra168.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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