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NITD-349

NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv.

Product Specifications

CAS Number

1473450-62-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/NITD-349.html

Purity

98.98

Solubility

DMSO : ≥ 310 mg/mL

Smiles

O=C(C(N1)=CC2=C1C=C(F)C=C2F)NC3CCC(C)(C)CC3

Molecular Formula

C17H20F2N2O

Molecular Weight

306.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Rao SP, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Sci Transl Med. 2013 Dec 4;5 (214) :214ra168.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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