MPP+ iodide
Product Specifications
CAS Number
36913-39-0
Target
Autophagy|||Mitochondrial Metabolism
Related Pathways
Autophagy|||Metabolism
Purity
0.9996
Bioactivity
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.
Smiles
[I-].C=1C=CC(=CC1)C=2C=C[N+](=CC2)C
Molecular Formula
C12H12IN
Molecular Weight
297.13
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1380698-01 0.05 mg (E-Coli)
Recombinant Pyrococcus kodakaraensis Elongation factor 1-alpha (tuf)
Ask
View Details MBS1380698-02 0.05 mg (Yeast)
Recombinant Pyrococcus kodakaraensis Elongation factor 1-alpha (tuf)
Ask
View Details MBS1380698-03 0.05 mg (Baculovirus)
Recombinant Pyrococcus kodakaraensis Elongation factor 1-alpha (tuf)
Ask
View Details