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XL177A

Product Specifications

CAS Number

2417089-74-6

Target

DUB

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination

Purity

0.9875

Bioactivity

XL177A is a selective irreversible USP7 inhibitor (IC50 : 0.34 nM) . XL177A elicits cancer cell killing through a p53-dependent mechanism.

Smiles

CN1CCN(CCC(=O)Nc2ccc3c(c2)ncn(CC2(O)CCN(CC2)C(=O)[C@@H](CCCNC(=O)c2ccc4c(Cl)c5CCCCc5nc4c2)Cc2ccccc2)c3=O)CC1

Molecular Formula

C48H57ClN8O5

Molecular Weight

861.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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