XL177A
Product Specifications
CAS Number
2417089-74-6
Target
DUB
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination
Purity
0.9875
Bioactivity
XL177A is a selective irreversible USP7 inhibitor (IC50 : 0.34 nM) . XL177A elicits cancer cell killing through a p53-dependent mechanism.
Smiles
CN1CCN(CCC(=O)Nc2ccc3c(c2)ncn(CC2(O)CCN(CC2)C(=O)[C@@H](CCCNC(=O)c2ccc4c(Cl)c5CCCCc5nc4c2)Cc2ccccc2)c3=O)CC1
Molecular Formula
C48H57ClN8O5
Molecular Weight
861.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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