What is the catalog number for Topovale?

The catalog number for Topovale is T9088.

What sizes are available for Topovale?

Topovale is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Topovale come in?

Topovale is available in 6 different pack sizes.

Is Topovale in stock?

Topovale is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Topovale?

Topovale is manufactured by Molfinity.

What is the estimated delivery time for Topovale?

Estimated delivery time for Topovale is approximately 10 business day(s), depending on your location.

Topovale

Product Specifications

CAS Number

500214-53-9

Target

Topoisomerase

Related Pathways

DNA Damage/DNA Repair

Purity

0.9994

Bioactivity

Topovale (ARC111) is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibited low nM cytotoxicity against a panel of cancer cells. Topovale cytotoxicity as well as Topovale-induced apoptosis was reduced > 100-fold in CPT-resistant topoisomerase I (TOP1) -deficient P388/CPT45 cells as compared with P388 cells.