AS1810722
Product Specifications
CAS Number
909561-15-5
Target
Cytochromes P450, STAT
Related Pathways
Metabolism, JAK/STAT signaling, Stem Cells
Purity
0.9913
Bioactivity
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate for research into allergic diseases, including asthma and atopic conditions.
Smiles
NC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1
Molecular Formula
C25H25F2N7O
Molecular Weight
477.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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