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AS1810722

Product Specifications

CAS Number

909561-15-5

Target

Cytochromes P450, STAT

Related Pathways

Metabolism, JAK/STAT signaling, Stem Cells

Purity

0.9913

Bioactivity

AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate for research into allergic diseases, including asthma and atopic conditions.

Smiles

NC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1

Molecular Formula

C25H25F2N7O

Molecular Weight

477.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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