JHU37152
Product Specifications
CAS Number
2369979-67-7
Target
AChR
Related Pathways
Neuroscience
Purity
0.9972
Bioactivity
JHU37152 (JHU 37152) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
Smiles
CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2cccc(F)c12
Molecular Formula
C19H20ClFN4
Molecular Weight
358.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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