JHU37160
Product Specifications
CAS Number
2369979-68-8
Target
AChR
Related Pathways
Neuroscience
Purity
0.9987
Bioactivity
JHU37160 (JHU 37160) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
Smiles
CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2c(F)cccc12
Molecular Formula
C19H20ClFN4
Molecular Weight
358.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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