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JHU37160

Product Specifications

CAS Number

2369979-68-8

Target

AChR

Related Pathways

Neuroscience

Purity

0.9987

Bioactivity

JHU37160 (JHU 37160) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.

Smiles

CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2c(F)cccc12

Molecular Formula

C19H20ClFN4

Molecular Weight

358.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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