AQX-016A
Product Specifications
CAS Number
849669-54-1
Target
Others, PI3K, Phosphatase, TNF
Related Pathways
PI3K/Akt/mTOR signaling, Others, Apoptosis, Metabolism
Bioactivity
AQX-016A is an orally active and potent SHIP1 agonist. It is a structural analog of pelorol and is three times more potent than the marine natural product pelorol at the same molar concentration. AQX-016A can activate recombinant SHIP1 enzyme in vitro and stimulate SHIP1 activity. It also inhibits the PI3K pathway and TNFa production, making it useful for various inflammatory diseases research [1] [2].
Smiles
[H][C@]12Cc3c(c(C)cc(O)c3O)[C@]1(C)CC[C@@]1([H])C(C)(C)CCC[C@]21C
Molecular Formula
C22H32O2
Molecular Weight
328.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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