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ML266

Product Specifications

CAS Number

1462267-08-8

Target

Glycosidase|||Glucosidase|||Glucokinase

Related Pathways

Metabolism

Purity

0.9958

Bioactivity

ML266, a glucocerebrosidase (GCase) chaperone with an IC50 of 2.5 µM, facilitates the transport of the mutant protein to the lysosome, thereby restoring GCase activity without inhibiting the enzyme's function. This compound shows promise for Gaucher disease research.

Smiles

CN(C(=O)CNC(=O)c1ccccc1OCC(=O)Nc1ccc(Br)cc1)c1ccccc1

Molecular Formula

C24H22BrN3O4

Molecular Weight

496.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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