ML266
Product Specifications
CAS Number
1462267-08-8
Target
Glycosidase|||Glucosidase|||Glucokinase
Related Pathways
Metabolism
Purity
0.9958
Bioactivity
ML266, a glucocerebrosidase (GCase) chaperone with an IC50 of 2.5 µM, facilitates the transport of the mutant protein to the lysosome, thereby restoring GCase activity without inhibiting the enzyme's function. This compound shows promise for Gaucher disease research.
Smiles
CN(C(=O)CNC(=O)c1ccccc1OCC(=O)Nc1ccc(Br)cc1)c1ccccc1
Molecular Formula
C24H22BrN3O4
Molecular Weight
496.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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