AEM1
Product Specifications
CAS Number
1030123-90-0
Target
Nrf2
Related Pathways
Immunology/Inflammation
Purity
0.9988
Bioactivity
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
Smiles
FC1=CC=C(C=C1)C1=CSC2=C1C(NCC1=CC=C3OCOC3=C1)=NC=N2
Molecular Formula
C20H14FN3O2S
Molecular Weight
379.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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