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AEM1

Product Specifications

CAS Number

1030123-90-0

Target

Nrf2

Related Pathways

Immunology/Inflammation

Purity

0.9988

Bioactivity

AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.

Smiles

FC1=CC=C(C=C1)C1=CSC2=C1C(NCC1=CC=C3OCOC3=C1)=NC=N2

Molecular Formula

C20H14FN3O2S

Molecular Weight

379.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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