PD-089828
Product Specifications
CAS Number
179343-17-0
Target
FGFR, EGFR, PDGFR, Src
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9739
Bioactivity
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
Smiles
CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl
Molecular Formula
C18H18Cl2N6O
Molecular Weight
405.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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