PD-089828

Product Specifications

CAS Number

179343-17-0

Target

FGFR|||EGFR|||PDGFR|||Src

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Purity

0.9739

Bioactivity

PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFR?, and EGFR (IC50s = 0.15, 1.76, and 5.47 ?M, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 ?M)

Smiles

CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl

Molecular Formula

C18H18Cl2N6O

Molecular Weight

405.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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