ML162
Product Specifications
CAS Number
1035072-16-2
Target
Ferroptosis|||Glutathione Peroxidase|||GPX
Related Pathways
Apoptosis|||Metabolism|||Oxidation-Reduction
Purity
0.9978
Bioactivity
ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity and selectively inhibits cell lines expressing mutant RAS oncogenes.
Smiles
COc1ccc(cc1Cl)N(C(C(=O)NCCc1ccccc1)c1cccs1)C(=O)CCl
Molecular Formula
C23H22Cl2N2O3S
Molecular Weight
477.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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HCST (DAP10, Hematopoietic Cell Signal Transducer, DNAX-activation Protein 10, Membrane Protein DAP10, Transmembrane Adapter Protein KAP10, KAP10, PIK3AP, UNQ587/PRO1157) discontinued
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