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TTA-A2

Product Specifications

CAS Number

953778-63-7

Target

Calcium Channel

Related Pathways

Metabolism|||Membrane transporter/Ion channel

Purity

0.999

Bioactivity

TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy.

Smiles

C[C@@H](NC(=O)Cc1ccc(cc1)C1CC1)c1ccc(OCC(F)(F)F)cn1

Molecular Formula

C20H21F3N2O2

Molecular Weight

378.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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