CID44216842
Product Specifications
CAS Number
1222513-26-9
Target
Ras, CDK
Related Pathways
GPCR/G Protein, MAPK, Cell Cycle/Checkpoint
Purity
0.9966
Bioactivity
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
Smiles
COc1cccc(c1)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)S(N)(=O)=O
Molecular Formula
C22H20BrN3O3S
Molecular Weight
486.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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