DOTMA
Product Specifications
CAS Number
104872-42-6
Target
Others, Liposome
Related Pathways
Others, Metabolism
Purity
0.9972
Bioactivity
DOTMA (N- (1- (2,3-dioleyloxy) propyl) -N, N, N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction.
Smiles
[Cl-].CCCCCCCC\C=C\CCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCC\C=C\CCCCCCCC
Molecular Formula
C42H84ClNO2
Molecular Weight
670.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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