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PF-543 hydrochloride

Product Specifications

CAS Number

1706522-79-3

Target

Apoptosis, Autophagy, S1P Receptor, LPL Receptor

Related Pathways

Autophagy, GPCR/G Protein, Apoptosis

Purity

0.9993

Bioactivity

PF-543 hydrochloride (PF-543) inhibits SphK1 with a K (i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

Smiles

Cl.Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1

Molecular Formula

C27H32ClNO4S

Molecular Weight

502.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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