MSA-2
Product Specifications
CAS Number
129425-81-6
Target
STING
Related Pathways
Immunology/Inflammation
Purity
0.9888
Bioactivity
MSA-2 is an orally available non-nucleotide STING agonist. The non-covalent dimer of MSA-2 binds to STING with nanomolar affinity. It shows anti-tumor activity in syngeneic mouse tumor models, synergizes with anti-PD-1, stimulates tumor secretion of interferon-β, induces tumor regression, and has long-lasting anti-tumor immunity. [3]
Smiles
COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O
Molecular Formula
C14H14O5S
Molecular Weight
294.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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