MM-102 TFA
Product Specifications
CAS Number
1883545-52-5
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9978
Bioactivity
MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor with an IC50 of 2.4 nM. This compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5), inhibiting MLL1 H3K4 histone methyltransferase (HMT) activity and down-regulating H3K4me3, which facilitates the epigenetic reprogramming of porcine somatic cell nuclear transfer embryos.
Smiles
OC(=O)C(F)(F)F.CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCC1)C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1
Molecular Formula
C37H50F5N7O6
Molecular Weight
783.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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