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G5-7

Product Specifications

CAS Number

939681-36-4

Target

Apoptosis, JAK

Related Pathways

Angiogenesis, JAK/STAT signaling, Stem Cells, Chromatin/Epigenetic, Apoptosis, Tyrosine Kinase/Adaptors

Purity

0.9937

Bioactivity

JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study

Smiles

CCOC(=O)N1C\C(=C\c2ccccc2F)C(=O)\C(C1)=C/c1ccccc1F

Molecular Formula

C22H19F2NO3

Molecular Weight

383.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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