CTPI-2
Product Specifications
CAS Number
68003-38-3
Target
Mitochondrial Metabolism
Related Pathways
Metabolism
Purity
0.9791
Bioactivity
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with (KD : 3.5 μM) . CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
Smiles
OC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O
Molecular Formula
C13H9ClN2O6S
Molecular Weight
356.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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